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Imaging the Retinal Vasculature
Annual Review of Vision Science ( IF 5.0 ) Pub Date : 2021-09-15 , DOI: 10.1146/annurev-vision-093019-113719
Stephen A Burns 1 , Ann E Elsner 1 , Thomas J Gast 1
Affiliation  

Advances in retinal imaging are enabling researchers and clinicians to make precise noninvasive measurements of the retinal vasculature in vivo. This includes measurements of capillary blood flow, the regulation of blood flow, and the delivery of oxygen, as well as mapping of perfused blood vessels. These advances promise to revolutionize our understanding of vascular regulation, as well as the management of retinal vascular diseases. This review provides an overview of imaging and optical measurements of the function and structure of the ocular vasculature. We include general characteristics of vascular systems with an emphasis on the eye and its unique status. The functions of vascular systems are discussed, along with physical principles governing flow and its regulation. Vascular measurement techniques based on reflectance and absorption are briefly introduced, emphasizing ways of generating contrast. One of the prime ways to enhance contrast within vessels is to use techniques sensitive to the motion of cells, allowing precise measurements of perfusion and blood velocity. Finally, we provide a brief introduction to retinal vascular diseases.

中文翻译:


视网膜血管成像

视网膜成像的进步使研究人员和临床医生能够对体内视网膜脉管系统进行精确的无创测量。这包括毛细血管血流量的测量、血流量的调节和氧气的输送,以及灌注血管的绘图。这些进步有望彻底改变我们对血管调节以及视网膜血管疾病治疗的理解。本综述概述了眼部血管系统功能和结构的成像和光学测量。我们包括血管系统的一般特征,重点是眼睛及其独特的地位。讨论了血管系统的功能,以及控制血流及其调节的物理原理。简要介绍了基于反射和吸收的血管测量技术,强调了产生对比度的方法。增强血管内对比度的主要方法之一是使用对细胞运动敏感的技术,从而能够精确测量灌注和血流速度。最后,我们对视网膜血管疾病进行简要介绍。

更新日期:2021-09-17
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