The maximum diameter of the balloon used for balloon dilatation(BD) of esophagogastric anastomotic stricture (EAS) is generally 20 millimeters. This study aimed to evaluate the safety and efficacy of BD under fluoroscopy, using balloons with a diameter of 25–30 millimeters. We retrospectively analyzed the data of patients with benign EAS treated by large BD (balloon diameter, 25–30 mm) under fluoroscopy. The Cox proportional hazards model (PHM) was used to identify the factors associated with stricture-free survival. The results show that a total of 127 patients were included in this study, and 204 BDs were performed. The technical success rate was 96.6%, and the clinical success rate was 99.2%. The incidence of serious adverse events was 3.4% (7/204). One patient died of massive hemorrhage during BD, and nine patients were lost to follow-up. For the remaining 117 patients, the median stricture-free survival period was 14.9 months. In multivariable analysis using the Cox PHM, only balloon diameter was significantly associated with stricture-free survival. The stricture-free survival period tended to increase as balloon diameter increased. Large BD under fluoroscopy appears to be safe and effective for the treatment of benign EAS after esophagectomy.

中文翻译：

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透视下大球囊扩张的安全性和有效性

用于食管胃吻合口狭窄（EAS）球囊扩张（BD）的球囊最大直径一般为20毫米。本研究旨在评估 BD 在透视下的安全性和有效性，使用直径为 25-30 毫米的球囊。我们回顾性分析了在透视下接受大 BD（球囊直径，25-30 mm）治疗的良性 EAS 患者的数据。Cox 比例风险模型 (PHM) 用于确定与无狭窄生存相关的因素。结果显示，本次研究共纳入127例患者，共进行了204次BDs。技术成功率为96.6%，临床成功率为99.2%。严重不良事件的发生率为 3.4% (7/204)。1 名患者在 BD 期间因大出血死亡，9 名患者失访。其余 117 名患者的中位无狭窄生存期为 14.9 个月。在使用 Cox PHM 的多变量分析中，只有球囊直径与无狭窄生存率显着相关。随着球囊直径的增加，无狭窄生存期趋于增加。透视下的大 BD 似乎对治疗食管切除术后良性 EAS 是安全有效的。