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A nod and a Wnk to axon branching and destruction
Neuron ( IF 16.2 ) Pub Date : 2021-09-16 , DOI: 10.1016/j.neuron.2021.08.027
Owen M Peters 1 , Gaynor A Smith 2
Affiliation  

In this issue of Neuron, Izadifar et al. (2021) have identified a conserved molecule Wnk as a key regulator in both developmental axon branching and long-term survival of neurons, characterizing its interplay with axon destruction genes including Sarm. The discovery of Wnk will be important to our understanding of neurodevelopmental and neurodegenerative diseases.



中文翻译:

对轴突分支和破坏的点头和Wnk

在本期《Neuron》中,Izadifar 等人。(2021) 发现了一种保守分子 Wnk 作为神经元发育轴突分支和长期存活的关键调节因子,描述了它与包括 Sarm 在内的轴突破坏基因的相互作用。Wnk 的发现对于我们理解神经发育和神经退行性疾病非常重要。

更新日期:2021-09-17
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