A novel catalyst has been afforded by attaching of a Cu(proline)₂ complex to magnetic nanoparticles through cheap, simple, and readily available chemicals. This catalyst was characterized by Fourier transform infrared, energy-dispersive X-ray, X-ray diffraction, vibrating-sample magnetometry, transmission electron microscopy, scanning electron microscopy, and inductively coupled plasma analyses. The catalytic activity of the Fe₃O₄@NH₂@TCT@HProCu nanocatalyst was investigated in a green and effective synthesis of pyran derivatives in high yields by applying three-component reactions of malononitrile, dimedone, and aldehydes in ethanol. Conversion was high under optimal conditions. The obtained nanocatalyst could be easily separated from the mixture of the reaction and was recyclable nine times via a simple magnet without considerable reduction of its catalytic efficiency. Operational simplicity, high product yields, environmental friendliness, ecofriendliness, economical processing, and easy workup are the features of this methodology.

中文翻译：

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用羟脯氨酸铜配合物功能化的磁性纳米颗粒作为一种高效、可回收和可回收的纳米催化剂：合成及其在串联 Knoevenagel-Michael 环缩聚反应中的催化应用

通过廉价、简单且容易获得的化学物质将 Cu(脯氨酸) ₂复合物连接到磁性纳米粒子上，提供了一种新型催化剂。该催化剂的特征在于傅里叶变换红外、能量色散 X 射线、X 射线衍射、振动样品磁强计、透射电子显微镜、扫描电子显微镜和电感耦合等离子体分析。Fe ₃ O ₄ @NH ₂的催化活性@TCT@HProCu 纳米催化剂通过在乙醇中应用丙二腈、二甲酮和醛的三组分反应，以高产率绿色有效地合成吡喃衍生物。在最佳条件下转化率高。获得的纳米催化剂可以很容易地从反应混合物中分离出来，并且可以通过一个简单的磁铁回收九次，而不会显着降低其催化效率。该方法的特点是操作简单、产品产量高、环境友好、生态友好、经济加工和易于处理。