Cigarette smoking is a risk factor of mortality and morbidity from various cancerous, respiratory, and myocardial diseases. Nicotine dependence is assessed based on the degree of physical dependence. We aimed to determine the clinical, socioeconomic and psychological factors associated with the smoking status and degree of nicotine dependence of smokers. From April 2009 to September 2010, we retrospectively collected data from 17,577 subjects aged ≥ 18 years who had undergone a general health examination at a health promotion center. The instruments used included the Fagerström Tolerance Questionnaire (FTQ), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), Stress Response Inventory (SRI), and Alcohol Use Disorder Identification Test (AUDIT). Of the current smokers (N = 3946), 2345 (59%), 1154 (29%), and 447 (12%) had low, moderate, and high nicotine dependence, respectively. In multiple logistic analysis, predictors of high nicotine dependence were male sex (odds ratio [OR] 3.705, 95% confidence interval [CI] 1.997–6.945), older age (≥ 65 years) (OR 1.016, 95% CI 1.004–1.029), higher body mass index (BMI) (OR 1.048, 95% CI 1.018–1.078), diabetes (OR 1.870, 95% CI 1.251–2.794), single marital status (OR 1.575, 95% CI 1.186–2.092), lower education level (OR 1.887, 95% CI 1.463–2.433), and a higher stress level (OR 1.018, 95% CI 1.997–6.945). Thus, clinical, psychological, socioeconomic status including male, older age, higher BMI, diabetes, single marital status, lower education, and higher stress should be taken into consideration by promoting smoking cessation.

吸烟是导致各种癌症、呼吸系统和心肌疾病死亡和发病的危险因素。尼古丁依赖是根据身体依赖程度来评估的。我们旨在确定与吸烟者的吸烟状况和尼古丁依赖程度相关的临床、社会经济和心理因素。从 2009 年 4 月至 2010 年 9 月，我们回顾性收集了 17,577 名 18 岁及以上在健康促进中心接受过一般健康检查的受试者的数据。使用的工具包括 Fagerström 耐受性问卷 (FTQ)、贝克抑郁量表 (BDI)、状态-特质焦虑量表 (STAI)、压力反应量表 (SRI) 和酒精使用障碍识别测试 (AUDIT)。目前吸烟者中（N = 3946)、2345 (59%)、1154 (29%) 和 447 (12%) 分别具有低、中和高尼古丁依赖性。在多重逻辑分析中，高尼古丁依赖的预测因素是男性（优势比 [OR] 3.705，95% 置信区间 [CI] 1.997–6.945）、年龄较大（≥ 65 岁）（OR 1.016，95% CI 1.004–1.029 )，较高的体重指数 (BMI)（OR 1.048，95% CI 1.018–1.078），糖尿病（OR 1.870，95% CI 1.251–2.794），单身婚姻状况（OR 1.575，95% CI 1.186–2.092），较低教育水平（OR 1.887，95% CI 1.463–2.433）和更高的压力水平（OR 1.018，95% CI 1.997–6.945）。因此，通过促进戒烟，应考虑临床、心理、社会经济状况，包括男性、年龄较大、BMI 较高、糖尿病、单身婚姻状况、受教育程度较低和压力较大。