Acinetobacter baumannii armed with multidrug resistance (MDR) and biofilm-forming ability is increasingly recognized as an alarming pathogen. A deeper comprehension of the correlation between these two armories is required in circumventing its infections. This study examined the biofilm-forming ability of the isolates by crystal violet staining and the antibiotic susceptibility by broth microdilution method. The genetic basis of the MDR and biofilm-forming phenotypes was screened by polymerase chain reaction. The antimicrobial activities of cinnamic and gallic acids against planktonic cells and biofilms of A. baumannii were investigated, and the findings were confirmed with scanning electron microscopy (SEM). Among 90 A. baumannii isolates, 69 (76.6%) were MDR, and all were biofilm formers; they were classified into weak (12.2%), moderate (53.3%), and strong (34.5%) biofilm formers. Our results underlined a significant association between MDR and enhanced biofilm formation. Genotypically, the presence of bla_VIM and bla_OXA–23 genes along with biofilm-related genes (ompA, bap, and csuE) was statistically associated with the biofilm-forming abilities. Impressively, both gallic and cinnamic acids could significantly reduce the MDR A. baumannii biofilms with variable degrees dependent on the phenotype–genotype characteristics of the tested isolates. The current findings may possess future therapeutic impact through augmenting antimicrobial arsenal against life-threatening infections with MDR A. baumannii biofilms.

鲍曼不动杆菌具有多药耐药性 (MDR) 和生物膜形成能力的生物越来越被认为是一种令人担忧的病原体。在规避其感染时，需要更深入地了解这两个军械库之间的相关性。本研究通过结晶紫染色检测分离物的生物膜形成能力，通过肉汤微量稀释法检测抗生素敏感性。MDR 和生物膜形成表型的遗传基础通过聚合酶链反应进行筛选。肉桂酸和没食子酸对浮游细胞和生物膜的抗菌活性鲍曼不动杆菌进行了调查，并通过扫描电子显微镜 (SEM) 证实了这一发现。90人之中鲍曼不动杆菌分离株中，69 个（76.6%）是 MDR，并且都是生物膜形成者；它们分为弱 (12.2%)、中度 (53.3%) 和强 (34.5%) 生物膜形成剂。我们的结果强调了 MDR 与增强的生物膜形成之间的显着关联。在基因型上，存在布拉_VIM和布拉_OXA-23基因以及生物膜相关基因（奥普一种， 巴普， 和 中央电视台E) 与生物膜形成能力在统计学上相关。令人印象深刻的是，没食子酸和肉桂酸都可以显着降低 MDR鲍曼不动杆菌不同程度的生物膜取决于测试分离株的表型 - 基因型特征。目前的研究结果可能通过增加针对 MDR 危及生命的感染的抗菌药物库而具有未来的治疗影响鲍曼不动杆菌 生物膜。