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Microbiome effects on immune surveillance of intestinal tumours
Nature Reviews Immunology ( IF 67.7 ) Pub Date : 2021-09-17 , DOI: 10.1038/s41577-021-00629-5
Kirsty Minton 1
Affiliation  

A new study explores the links between diet and colorectal cancer risk by showing that changes to the intestinal microbiome in mice fed a high-fat diet result in attenuated MHC class II expression by intestinal stem cells and hence impaired immune surveillance of tumour initiation.

中文翻译:

微生物组对肠道肿瘤免疫监视的影响

一项新研究通过显示喂食高脂肪饮食的小鼠肠道微生物组的变化导致肠道干细胞的 MHC II 类表达减弱,从而削弱了对肿瘤起始的免疫监视,从而探索了饮食与结直肠癌风险之间的联系。
更新日期:2021-09-17
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