Bovine enteric disease has a complex etiology that can include viral, bacterial, and parasitic pathogens and is a significant source of losses due to morbidity and mortality. Boosepivirus was identified in calves with enteric disease with unclear etiology in Japan in 2009 and has not been reported elsewhere. Metagenomic sequencing and PCR here identified boosepivirus in bovine enteric disease diagnostic submissions from six states in the USA with 98% sequence identity to members of the species Boosepivirus B. In all cases, boosepivirus was identified as a coinfection with the established pathogens bovine coronavirus, bovine rotavirus, and cryptosporidia. Further research is needed to determine the clinical significance of boosepivirus infection.

牛肠道疾病具有复杂的病因，包括病毒、细菌和寄生虫病原体，是发病率和死亡率造成损失的重要来源。2009 年，日本在病因不明的肠道疾病小牛身上发现了布斯皮病毒，其他地方未见报道。宏基因组测序和 PCR 在美国六个州提交的牛肠道疾病诊断报告中鉴定出布斯皮病毒，与布斯皮病毒 B物种的成员有 98% 的序列同一性。在所有情况下，boosepivirus 都被确定为与既定病原体牛冠状病毒、牛轮状病毒和隐孢子虫共同感染。需要进一步的研究来确定布斯皮病毒感染的临床意义。