Objective The excess of visceral adipose tissue might hinder and delay the immune response. How people with abdominal obesity will respond to mRNA vaccines against SARS-CoV-2 is yet to be established. We evaluated SARS-CoV-2-specific antibody responses after the first and second dose of the BNT162b2 mRNA vaccine comparing the response of individuals affected by abdominal obesity (AO) to those without, discerning between individuals with or without prior infection.

中文翻译：

---

对 BNT162b2 mRNA 疫苗的抗体反应：腹部肥胖的未感染个体值得关注

目的内脏脂肪组织过多可能阻碍和延缓免疫反应。腹型肥胖患者对 SARS-CoV-2 mRNA 疫苗的反应尚待确定。我们在第一剂和第二剂 BNT162b2 mRNA 疫苗后评估了 SARS-CoV-2 特异性抗体反应，比较了受腹型肥胖 (AO) 影响的个体与未受腹型肥胖 (AO) 影响的个体的反应，区分有或没有先前感染的个体。