Purpose

To evaluate whether arterial and venous color-coded mCTA score may predict clinical outcome in anterior circulation acute ischemic stroke.

Methods

Consecutive patients referred to the emergency department with anterior circulation acute ischemic stroke (AIS) were retrospectively reviewed at our center. All patients underwent multimodal brain computed tomography (CT) imaging, including non-contrast CT (NCCT) and multiphase computed tomography angiography (mCTA). Baseline collateral scores of color-coded mCTA, also known as ColorViz, and conventional mCTA were recorded. mCTA was assessed by a 6-point scale whereas color-coded mCTA was assessed by a 3-point scale. In the Color-coded maps, a different color is assigned to intracranial vessels based on the arrival time of the contrast medium and on a per-person adaptive threshold technique. We compared the radiological and clinical features of a group of patients who reached independency (defined as modified Rankin Scale score ≤ 2) with those of patients who did not. A multivariate logistic regression model was then used to assess the potential of color-coded mCTA scores to predict patients' outcome after AIS.

Results

A total of 86 patients (36 M, 50 F) were enrolled in the study. Multivariate logistic regression showed that score 3 at Color-coded mCTA was a good predictor of favorable outcome (p = 0.003). Moreover, NIHSS at onset (p = 0.004) and discharge (p < 0.001) along with ischemic core area (p = 0.011) were significant predictors of favorable prognosis.

Conclusion

our data confirm that ColorViz is a useful and easily understandable neuroimaging tool that might have a predictive role in assessing the outcome of anterior circulation acute ischemic stroke patients regardless of revascularization therapy.

中文翻译：

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彩色编码多相计算机断层扫描血管造影可预测前循环急性缺血性卒中的预后

目的

评估动脉和静脉颜色编码的 mCTA 评分是否可以预测前循环急性缺血性卒中的临床结果。

方法

我们中心对连续因前循环急性缺血性卒中 (AIS) 转诊至急诊科的患者进行了回顾性研究。所有患者均接受了多模式脑计算机断层扫描 (CT) 成像，包括非对比 CT (NCCT) 和多相计算机断层扫描血管造影 (mCTA)。记录颜色编码的 mCTA（也称为 ColorViz）和常规 mCTA 的基线附属分数。mCTA 由 6 分制评估，而颜色编码的 mCTA 由 3 分制评估。在彩色编码的地图中，根据造影剂的到达时间和每个人的自适应阈值技术，为颅内血管分配不同的颜色。我们比较了一组达到独立（定义为改良 Rankin 量表评分≤ 2）的患者与未达到独立的患者的放射学和临床特征。然后使用多变量逻辑回归模型来评估颜色编码的 mCTA 评分预测 AIS 后患者结果的潜力。

结果

共有 86 名患者（36 M，50 F）参加了该研究。多变量逻辑回归显示，彩色编码 mCTA 的 3 分是良好结果的良好预测指标 ( p  = 0.003)。此外，NIHSS 发病 ( p  = 0.004) 和出院 ( p  <0.001) 以及缺血核心区 ( p  = 0.011) 是预后良好的重要预测因素。

结论

我们的数据证实 ColorViz 是一种有用且易于理解的神经影像工具，无论是否进行血运重建治疗，它都可能在评估前循环急性缺血性卒中患者的预后方面具有预测作用。