Cardiovascular diseases can affect the clinical course of coronavirus disease 2019 (COVID-19); however, evaluation of COVID-19 contribution to prognosis for each individual disease, such as heart failure, is lacking in South Korea. Therefore, this study aimed to investigate COVID-19 patients with heart failure by matching them with patients with heart failure only and those with COVID-19 only. We performed a nationwide population-based retrospective study using data from the National Health Insurance System. Based on patients with heart failure and COVID-19, up to 1:3 propensity score matching procedures were performed for patients with heart failure only and those with COVID-19 only. The outcome was the composite of complications. After matching, a multivariable-adjusted conditional logistic regression analysis was performed. The number of patients was 317 for heart failure and COVID-19, 951 for heart failure only, and 884 for COVID-19 only. The adjusted odds ratio (OR) and 95% confidence interval (CI) for the composite of complications of patients with heart failure and COVID-19 compared with those with heart failure only was 3.511 (2.501-4.928), and compared with those with COVID-19 only, they were 1.626 (1.112-2.376). In patients with heart failure and COVID-19, age per 10 years increase and diabetes were significant variables with the adjusted OR (95% CI) [2.206 (1.704-2.856) for age and 2.345 (1.244-4.420) for diabetes] for complications. This study demonstrated that patients with both heart failure and COVID-19 in South Korea are associated with a poor prognosis. Patients with heart failure require more surveillance and precautions for COVID-19, as recommended by the Center for Disease Control and Prevention.

心血管疾病会影响 2019 冠状病毒病 (COVID-19) 的临床病程；然而，韩国缺乏对 COVID-19 对每种疾病（如心力衰竭）预后影响的评估。因此，本研究旨在通过将 COVID-19 患者与仅患有心力衰竭的患者和仅患有 COVID-19 的患者进行匹配来调查患有心力衰竭的 COVID-19 患者。我们使用来自国民健康保险系统的数据进行了一项全国性的基于人群的回顾性研究。基于心力衰竭和 COVID-19 的患者，对仅患有心力衰竭的患者和仅患有 COVID-19 的患者进行了高达 1:3 的倾向评分匹配程序。结果是并发症的复合。匹配后，进行多变量调整的条件逻辑回归分析。心力衰竭和 COVID-19 的患者人数为 317 人，仅心力衰竭患者为 951 人，仅 COVID-19 患者为 884 人。心力衰竭合并 COVID-19 患者与仅心力衰竭患者相比，调整后的优势比 (OR) 和 95% 置信区间 (CI) 为 3.511 (2.501-4.928)，并与 COVID-19 患者相比仅 -19，它们是 1.626 (1.112-2.376)。在心力衰竭和 COVID-19 患者中，年龄每 10 年增加和糖尿病是显着变量，调整后的 OR（95% CI）[年龄为 2.206 (1.704-2.856)，糖尿病为 2.345 (1.244-4.420)] 并发症. 这项研究表明，韩国同时患有心力衰竭和 COVID-19 的患者预后较差。心力衰竭患者需要更多的 COVID-19 监测和预防措施，