GUN4 regulates chlorophyll biosynthesis and chloroplast-to-nucleus signaling by binding to a variety of tetrapyrrole molecules. In this cover image, six known GUN4 ligands are shown, including cyclic (black) and open-chain (green-blue) tetrapyrroles. The biliverdin-bound GUN4 structure is presented in surface model with the ligand in gray stick. The figure was created by Lin Liu. See article by Hu et al., pp. 2083—2091.

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封面图片

GUN4 通过与多种四吡咯分子结合来调节叶绿素生物合成和叶绿体到细胞核的信号传导。在这张封面图片中，显示了六个已知的 GUN4 配体，包括环状（黑色）和开链（绿-蓝）四吡咯。结合胆绿素的 GUN4 结构呈现在表面模型中，配体呈灰色棒状。该图是由林柳创作的。参见 Hu 等人的文章，第 2083-2091 页。