The pollution of water with heavy metal ions has generated great concern among both the public and academics due to the high toxicity, persistence, and non-degradability of heavy metals. The detection, detoxification, and removal of heavy metal ions are critical for monitoring water quality and treating polluted water. However, these tasks remain challenging due to lack of effective detection, detoxification, and removal strategies. By combining thiol-triggered click chemistry and heavy metal ion-triggered declick chemistry, a recyclable fluorescent probe for detecting numerous heavy metal ions was successfully developed through simple addition of thiol-containing heavy metal antidote to a carefully selected Michael acceptor-type fluorophore. The probe could be regenerated by adding equal amount of antidote to the detection solution without any purification step recycled up to 10 times. The generated water-soluble heavy metal ion–antidote complexes showed weak toxicity to biological systems, indicating successful detoxification. Finally, a simple, economical, and practical device for detecting, detoxifying, and removing heavy metal ions was fabricated by loading the recyclable fluorescent probe into polymer beads. The percent of detection, and removal are 98.10% and 97.59%, respectively. And detoxification percent is as high as 65.55%. The device is a promising candidate for water quality monitoring and treatment.

由于重金属的高毒性、持久性和不可降解性，重金属离子对水体的污染引起了公众和学术界的极大关注。重金属离子的检测、解毒和去除对于监测水质和处理污染水至关重要。然而，由于缺乏有效的检测、解毒和清除策略，这些任务仍然具有挑战性。通过结合硫醇触发的点击化学和重金属离子触发的去点击化学，通过简单地将含硫醇的重金属解毒剂添加到精心挑选的迈克尔受体型荧光团中，成功开发了一种用于检测大量重金属离子的可回收荧光探针。探针可以通过向检测溶液中加入等量的解毒剂来再生，无需任何纯化步骤，循环使用多达 10 次。生成的水溶性重金属离子-解毒剂复合物对生物系统的毒性较弱，表明解毒成功。最后，通过将可回收荧光探针加载到聚合物珠中，制备了一种简单、经济、实用的重金属离子检测、解毒和去除装置。检测百分比和去除百分比分别为 98.10% 和 97.59%。并且解毒百分比高达65.55%。该设备是水质监测和处理的有前途的候选者。说明排毒成功。最后，通过将可回收荧光探针加载到聚合物珠中，制备了一种简单、经济、实用的重金属离子检测、解毒和去除装置。检测百分比和去除百分比分别为 98.10% 和 97.59%。并且解毒百分比高达65.55%。该设备是水质监测和处理的有前途的候选者。说明排毒成功。最后，通过将可回收荧光探针加载到聚合物珠中，制备了一种简单、经济、实用的重金属离子检测、解毒和去除装置。检测百分比和去除百分比分别为 98.10% 和 97.59%。并且解毒百分比高达65.55%。该设备是水质监测和处理的有前途的候选者。