Multiple intra-atrial thrombi are found rarely except in the presence of prosthetic valves, intra-cardiac devices, structural connections like foramen ovale and thrombophilia. We reported acute thrombosis formation in right and left atrial appendages of a 66-year old man admitted due to progressive dyspnea since 7 days earlier. He had a history of prior laryngeal Squamous Cell Carcinoma, apical hypertrophic cardiomyopathy (HCM), and atrial fibrillation (AF). Infection with COVID-19 was confirmed thereafter. Cardiac Magnetic Resonance Imaging (CMR) suggested the diagnosis of atrial clot superior to neoplasm. After surgical removal of the thrombi, symptoms as well as imaging features of pneumonia were resolved. We should focus on different presentations and complications of systemic inflammation especially in the setting of COVID-19 infection. Although risk factors of thrombosis are present in some of these patients, rapid progression as well as unusual types of involvement may indicate to a new trigger.

中文翻译：

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COVID-19 感染与左右心耳大血栓的关联

除了存在人工瓣膜、心脏内装置、卵圆孔和血栓形成倾向等结构性连接外，很少发现多发性心房内血栓。我们报告了一名 66 岁男性自 7 天前因进行性呼吸困难入院的右心耳和左心耳急性血栓形成。他既往有喉鳞状细胞癌、心尖肥厚性心肌病 (HCM) 和心房颤动 (AF) 病史。此后确认感染了 COVID-19。心脏磁共振成像 (CMR) 提示心房凝块的诊断优于肿瘤。手术切除血栓后，肺炎的症状和影像学特征得到解决。我们应该关注全身炎症的不同表现和并发症，尤其是在 COVID-19 感染的情况下。