There is currently a dramatic increase in the number of COVID-19 cases worldwide, and further drastic restrictions in our daily life will be necessary to contain this pandemic. The implications of restrictive measures like social-distancing and mouth-nose protection on patients with chronic respiratory diseases have hardly been investigated. Our survey, was conducted within the All Age Asthma Cohort (ALLIANCE), a multicenter longitudinal observational study. We assessed the effects of COVID-19 imposed social isolation and use of facial masks, on asthma course and mental health in patients with asthma and wheezing. We observed a high rate of problems associated with using facemasks and a significant reduction in the use of routine medical care. In addition to unsettling impacts, such as an increase in depression symptoms in adults, an astonishing and pleasing effect was striking: preschool children experienced an improvement in disease condition during the lockdown. This improvement can be attributed to a significant reduction in exposure to viral infections. Long-term observation of this side effect may help improve our understanding of the influence of viral infections on asthma in early childhood.

中文翻译：

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强加社会隔离和使用口罩对儿童和成人复发性喘息和哮喘患者的哮喘病程和心理健康的影响

目前，全球 COVID-19 病例数量急剧增加，为了遏制这种流行病，需要对我们的日常生活进行进一步的严格限制。几乎没有研究过社交距离和口鼻保护等限制性措施对慢性呼吸道疾病患者的影响。我们的调查是在全年龄哮喘队列 (ALLIANCE) 内进行的，这是一项多中心纵向观察研究。我们评估了 COVID-19 强加于社会隔离和使用口罩对哮喘和喘息患者的哮喘病程和心理健康的影响。我们观察到与使用口罩相关的问题发生率很高，并且日常医疗护理的使用显着减少。除了令人不安的影响，例如成年人抑郁症状的增加，令人惊讶和令人愉悦的效果是惊人的：学龄前儿童在封锁期间疾病状况有所改善。这种改善可归因于暴露于病毒感染的显着减少。长期观察这种副作用可能有助于提高我们对病毒感染对儿童早期哮喘影响的理解。