The synergistic integration of optofluidic and surface enhanced Raman scattering (SERS) sensing is a new analytical technique that provides a number of unique characteristics for enhancing the sensing performance and simplifying the design of microsystems. Here, we propose a reusable optofluidic SERS sensor by integrating Au nanoisland substrate (AuNIS)-coated fiber into a microfluidic chip. Through both systematic experimental and theoretical analysis, the sensor enables efficient self-cleaning based on its optical-to-heat-hydrodynamic energy conversion property. Besides, the sensor exhibits the instrument detection limit down to ${{10}^{- 13}}\;{\rm mol}/{\rm L}$ and enhancement factor of ${{10}^6}$ for Rhodamine 6G. Our optofluidic SERS sensor with such a photothermal microfluidic-assisted self-cleaning method has the advantages of portability, simple operation, and high cleaning efficiency, which will provide a new, to the best of our knowledge, concept and approach for cost-effective and reusable sensors.

中文翻译：

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用于高度可重复使用的 SERS 传感器的光热微流体辅助自清洁效应

光流体和表面增强拉曼散射 (SERS) 传感的协同集成是一种新的分析技术，它提供了许多独特的特性，可提高传感性能并简化微系统的设计。在这里，我们通过将 Au 纳米岛基底 (AuNIS) 涂层光纤集成到微流控芯片中，提出了一种可重复使用的光流控 SERS 传感器。通过系统的实验和理论分析，该传感器基于其光热流体能量转换特性实现了高效的自清洁。此外，该传感器的仪器检测限低至${{10}^{- 13}}\;{\rm mol}/{\rm L}$和增强因子${{10}^6}$罗丹明 6G。我们采用这种光热微流体辅助自清洁方法的光流控 SERS 传感器具有便携、操作简单和清洁效率高的优点，这将为我们提供一种新的，尽我们所知，具有成本效益的概念和方法。可重复使用的传感器。