Objective. We sought to analyze the distribution and antibiotic sensitivity of pathogens in hospitalized patients and to provide a scientific reference for the rational application of antibiotics. Methods. From January 2014 to December 2018, urine cultures from patients in our hospital were collected and analyzed retrospectively for the presence, distribution, and drug sensitivity of pathogens. Results. A total of 42,854 midstream urine cultures were collected from which 11,891 (27.75%) pathogens were isolated, including 8101 (68.13%) strains of gram-negative bacteria, 2580 (21.69%) strains of gram-positive bacteria, and 1210 (10.18%) strains of fungi. Escherichia coli and Enterococci were the most common species of gram-negative and gram-positive bacteria, respectively. Drug sensitivity varied among different pathogens. Clear drug resistance was observed in bacteria, while fungus exhibited relatively lower resistance. Conclusion. Pathogens responsible for urinary tract infections in hospitalized patients are diversiform and display resistance to some antibiotics. Drug resistance monitoring should be enhanced to optimize antimicrobial therapy.

中文翻译：

---

2014-2018年住院患者尿培养：病原菌分布及药物敏感性分析

客观。旨在分析住院患者病原菌分布及抗生素敏感性，为合理应用抗生素提供科学参考。方法。收集2014年1月至2018年12月我院患者尿培养，回顾性分析病原菌的存在、分布及药敏情况。结果。共采集中游尿培养42854份，分离出病原菌11891株（27.75%），其中革兰氏阴性菌8101株（68.13%）、革兰氏阳性菌2580株（21.69%）、革兰氏阳性菌1210株（10.18%） ) 真菌菌株。大肠杆菌和肠球菌分别是最常见的革兰氏阴性菌和革兰氏阳性菌。不同病原体的药物敏感性不同。在细菌中观察到明显的耐药性，而真菌表现出相对较低的耐药性。结论。导致住院患者尿路感染的病原体多种多样，并对某些抗生素表现出耐药性。应加强耐药性监测以优化抗菌治疗。