Background

Healthcare professionals (HCPs) are at the front line of the nation’s fight against COVID-19 and are always at a greater risk of contracting contagious disease. But amidst the crisis, the vaccines were not accepted by all the HCPs due to adverse events occurring post-COVID-19 vaccination. Hence, the present study was designed to assess adverse events occurring among HCPs post-COVID-19 vaccination both quantitatively and qualitatively.

Method

Sequential mixed-method approach was employed. A cross-sectional E-survey was conducted among the healthcare professionals of a North Indian (*Statistically significant (p < 0.05)) college and hospital. The second phase included a semi-structured qualitative interview of the participants who were willing to participate.

Results

Among all the HCPs with age groups ranging from 20 to 70 years, majority of them experienced pain at the site of injection (88.8–100%) followed by tiredness (87.7–60%) and body ache (86.6–40%) post-vaccination. There is an increased frequency of adverse events in females as compared to males. Qualitative findings are summarised in three major domains i.e vaccine adverse effects, fear and hesitancy for vaccines and vaccine acceptance.

Conclusion

Short term adverse events of COVISHIELD vaccine were very few and were mild in severity yet interviews showed hesitancy of study participants for vaccination.

中文翻译：

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医疗保健专业人员接种 covid-19 疫苗后发生的不良事件——一项混合方法研究

背景

医疗保健专业人员 (HCP) 处于国家抗击 COVID-19 的前线，并且总是处于感染传染病的更大风险中。但在危机中，由于 COVID-19 疫苗接种后发生的不良事件，疫苗并未被所有 HCP 接受。因此，本研究旨在定量和定性地评估 HCP 接种 COVID-19 疫苗后发生的不良事件。

方法

采用顺序混合方法。在北印度（*具有统计意义 (p < 0.05)）大学和医院的医疗保健专业人员中进行了一项横断面电子调查。第二阶段包括对愿意参与的参与者进行半结构化定性访谈。

结果

在 20 至 70 岁的所有 HCP 中，大多数人在注射后经历了注射部位疼痛 (88.8–100%)，其次是疲倦 (87.7–60%) 和身体疼痛 (86.6–40%)接种疫苗。与男性相比，女性发生不良事件的频率更高。定性研究结果概括为三个主要领域，即疫苗不良反应、对疫苗的恐惧和犹豫以及疫苗接受度。

结论

COVISHIELD 疫苗的短期不良事件很少且严重程度较轻，但访谈显示研究参与者对接种疫苗犹豫不决。