The depolarization of the postsynaptic membrane potential in neuromuscular junction, which is conducted by the (stochastic) opening of nicotinic acetylcholine (nACh) receptors distributed in postsynaptic folds, is an inevitable stage in transmitting the electric signals from neural ends to muscle fibers. To perform this work, free energy must be dissipated. Being the first step in understanding the speech-accuracy-energy trade-off, we calculate the energy dissipation of a tiny membrane system that contains a single nACh receptor, i which firstly the stationary distribution of voltage is calculated based on our new method on solving the high-dimensional ODEs with variable coefficients. The ratio of the extent of depolarized-potential to the dissipated power is used to characterize the energy consuming efficiency of the system.

神经肌肉接头中突触后膜电位的去极化是由分布在突触后皱襞中的烟碱型乙酰胆碱 (nACh) 受体的（随机）打开进行的，是将电信号从神经末端传递到肌肉纤维的必然阶段。为了完成这项工作，必须消耗自由能。作为理解语音-准确度-能量权衡的第一步，我们计算了一个包含单个 nACh 受体的微小膜系统的能量耗散，首先基于我们解决问题的新方法计算电压的平稳分布具有可变系数的高维 ODE。去极化电位的程度与耗散功率的比值用于表征系统的能量消耗效率。