Recent studies showed that plant extracts enhance the antibacterial activity of conventional antibiotics. Those extracts could be used to synthesize nanoparticles for producing antibiotics with better results against microbial infections. We selected the medicinal plant Argemone mexicana L. and evaluated its antibacterial activity. An extract of this plant was used for synthesizing gold and silver nanoparticles. The antibacterial activity of nanoparticles was tested against pathogenic bacteria by the Kirby-Bauer protocol. Strains bacteria were obtained directly from clinical isolates from a Hospital in Mexico. SEM analysis indicates that A. mexicana L. extract allows the synthesis of Au and Ag nanoparticles. Results indicate that the organic molecules from the extract and the Ag nanoparticles act synergically to increase inhibition effect in the growth of resistant bacteria, wild type bacteria and Candida albicans. In conclusion, the Ag nanoparticles obtained by A. mexicana L. extract have an excellent performance against antibiotic-resistant bacteria from a hospital environment, and in consequence, they have the potential to be used for producing more efficient antibiotics.

最近的研究表明，植物提取物可增强常规抗生素的抗菌活性。这些提取物可用于合成纳米颗粒，用于生产抗生素，对微生物感染有更好的效果。我们选择了药用植物蓟罂粟大号。并评价其抗菌活性。这种植物的提取物用于合成金和银纳米粒子。通过 Kirby-Bauer 协议测试了纳米颗粒对病原菌的抗菌活性。菌株细菌直接从墨西哥一家医院的临床分离株中获得。SEM 分析表明A. mexicanaL. 提取物允许合成 Au 和 Ag 纳米粒子。结果表明，提取物中的有机分子和银纳米颗粒协同作用，增加了对耐药菌、野生型细菌和白色念珠菌生长的抑制作用。总而言之，由A. mexicana L. 提取物获得的银纳米粒子对医院环境中的抗生素耐药细菌具有优异的性能，因此，它们有可能用于生产更有效的抗生素。