Continuous-flow techniques have promoted the development of synthetic chemistry due to advantages such as outstanding mass/heat transfer, on-demand scalability, improved safety, precise regulation on reaction parameters, etc. Recently, the combination of flow polymerization with computer science has gained considerable interests, leading to a variety of cutting-edge synthetic techniques. This review summarizes emerging achievements realized via the integration of computer science and living flow polymerizations, including 1) high-throughput living polymerizations in flow, 2) programmable regulations of dispersity profile, sequence and topology for polymers, 3) modular design with online monitoring, as well as 4) self-optimized living polymerizations in flow. We expect that this summary will furnish informative knowledge to scientists in related directions and inspire new ideas to further empower on-demand polymer engineering with modern techniques.

中文翻译：

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在连续流动条件下进行的计算机辅助活性聚合†

连续流动的技术，促进了合成化学的发展由于诸如优秀传质/传热，按需可扩展性，提高的安全性，在反应参数的精确调节，优点等. 最近，流动聚合与计算机科学的结合引起了人们极大的兴趣，从而产生了各种尖端的合成技术。本综述总结了通过计算机科学和活性流动聚合的整合所实现的新兴成就，包括 1) 流动中的高通量活性聚合，2) 聚合物的分散分布、序列和拓扑结构的可编程规则，3) 具有在线监测的模块化设计，以及 4) 流动中自我优化的活性聚合。我们希望本摘要能够为相关方向的科学家提供丰富的知识，并激发新的想法，以利用现代技术进一步增强按需聚合物工程的能力。