The local concentration effect on the adherence of Escherichia coli 83972 was evaluated using mannosylated PAMAM dendrimers with varying concentrations to immobilize on the surfaces. Results showed no enhancement in adherence by Escherichia coli 83972 using a high local concentration of biphenyl mannoside immobilized on the PAMAM surfaces. The separation distance rather than the local multivalency of the ligand-receptor binding plays an essential role in this system. A vertical orientation of bacteria during the initial binding process was proposed that allows the mobility of bacteria to efficiently survey the environment for potential binding sites.

中文翻译：

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大肠杆菌 83972 在呈递 α-联苯甘露糖苷的 PDMS 表面粘附的研究

使用不同浓度的甘露糖化 PAMAM 树枝状聚合物固定在表面上，评估了局部浓度对大肠杆菌83972粘附的影响。结果表明，使用固定在 PAMAM 表面上的局部高浓度联苯甘露糖苷对大肠杆菌83972 的粘附没有增强。配体-受体结合的分离距离而不是局部多价在该系统中起着重要作用。提出了在初始结合过程中细菌的垂直方向，允许细菌的移动性有效地调查潜在结合位点的环境。