Duchenne muscular dystrophy (DMD), an X-linked childhood-onset muscular dystrophy caused by loss of the protein dystrophin, can be associated with neurodevelopmental, emotional and behavioural problems. A DMD mouse model also displays a neuropsychiatric phenotype, including increased startle responses to threat which normalise when dystrophin is restored in the brain.

中文翻译：

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在杜氏肌营养不良症中开发一种新的惊吓反应任务

Duchenne 肌营养不良症 (DMD) 是一种由肌营养不良蛋白丢失引起的 X 连锁儿童期肌营养不良症，可能与神经发育、情绪和行为问题有关。DMD 小鼠模型还显示出神经精神病学表型，包括对威胁的惊吓反应增加，当肌营养不良蛋白在大脑中恢复时会恢复正常。