Robert Rosen’s relational biology and biosemiotics share the claim that life cannot be explained by the laws that apply to the inanimate world alone. In this paper, an integrated account of Rosen’s relational biology and Peirce’s semiosis is proposed. The ultimate goal is to contribute to the construction of a unified framework for the definition and study of life. The relational concepts of component and mapping, and the semiotic concepts of sign and triadic relation are discussed and compared, and a representation of semiotic relations with mappings is proposed. The role of the final cause in two theories that account for what differentiates living beings, natural selection and relational biology, is analyzed. Then the presence of the final cause in Peirce’s semiosis is discussed and, with it, the similarities and differences between the theories of Rosen and Peirce are deepened. Then, a definition of a semiotic relation in an organism is proposed, and Short’s definition of interpretation is applied. Finally, a method to identify and analyze semiotic actions in an organism is proposed.

罗伯特·罗森 (Robert Rosen) 的关系生物学和生物符号学都认为生命不能仅用适用于无生命世界的定律来解释。在本文中，提出了对罗森关系生物学和皮尔斯符号学的综合解释。最终目标是为构建一个统一的生命定义和研究框架做出贡献。讨论和比较了分量和映射的关系概念，符号和三元关系的符号概念，并提出了用映射表示符号关系。分析了最终原因在解释生物的区别的两种理论中的作用，即自然选择和关系生物学。然后讨论了 Peirce 符号学中最终原因的存在，并与它一起，加深了罗森和皮尔斯理论之间的异同。然后，提出了有机体中符号学关系的定义，并应用了肖特的解释定义。最后，提出了一种识别和分析生物体中符号行为的方法。