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Electricity Driven 1,3-Oxohydroxylation of Donor-Acceptor Cyclopropanes: a Mild and Straightforward Access to β-Hydroxy Ketones
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2021-09-15 , DOI: 10.1002/ejoc.202101022
Debarshi Saha 1 , Irshad Maajid Taily 1 , Prabal Banerjee 2
Affiliation  

A facile protocol entailing the principle of electrochemical oxidation of aryl rings has been utilized to relieve the strain of donor-acceptor cyclopropane and further trap the molecular oxygen to deliver the 1,3-bifunctionalized product. Hence, the methodology bestows a novel route towards the scalable synthesis of β-hydroxy ketones.
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中文翻译:

供体-受体环丙烷的电力驱动 1,3-氧代羟基化:温和而直接地获得 β-羟基酮

一种采用芳环电化学氧化原理的简便方案已被用于减轻供体-受体环丙烷的应变,并进一步捕获分子氧以提供 1,3-双功能化产物。因此,该方法为β-羟基酮的可扩展合成提供了一条新途径。
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更新日期:2021-09-27
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