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Effects of menthol on esophageal motility in humans: Studies using high-resolution manometry
Neurogastroenterology & Motility ( IF 3.5 ) Pub Date : 2021-09-14 , DOI: 10.1111/nmo.14267
Wei-Yi Lei, Shu-Wei Liang, Jui-Sheng Hung, Ming-Wun Wong, Tso-Tsai Liu, Chih-Hsun Yi, Lin Lin, William C. Orr, Chien-Lin Chen

The cold receptor, transient receptor potential melastatin 8 (TRPM8), has been reported to be expressed in esophageal vagal afferents. Esophageal infusion of menthol modulates esophageal perception in reflux patients via TRPM8, but the effects of menthol on esophageal motility are not well investigated. This study aimed to test the hypothesis whether the infusion of menthol into the esophagus could affect esophageal peristaltic characteristics.

中文翻译:

薄荷醇对人类食管运动的影响:使用高分辨率测压法的研究

据报道,冷受体、瞬时受体电位 melastatin 8 (TRPM8) 在食管迷走神经传入神经中表达。薄荷醇的食管输注通过 TRPM8 调节反流患者的食管感知,但薄荷醇对食管动力的影响尚未得到很好的研究。本研究旨在检验薄荷醇注入食道是否会影响食道蠕动特性的假设。
更新日期:2021-09-14
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