Multiple sclerosis (MS) is a chronic disease, with fatigue syndrome as one of the main symptoms. The aim of this study was to demonstrate that moderate physical activity (MPA) may have a beneficial effect on postural stability, balance, and clinical parameters. The research group consisted of 137 randomized patients hospitalized at the Department of Neurological Rehabilitation, Medical University of Lodz. Finally, 76 patients were qualified who were divided into two groups—high fatigue (HF) and low fatigue (LF). Participants were assessed twice: before and after a 4-week MPA program using: the Expanded Disability Status Scale (EDSS), the Fatigue Severity Scale (FSS), the Mini-Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), the Beck Depression Inventory (BDI), and the Geriatric Depression Scale (GDS), and stabilometric platform tests were performed. Results obtained after the 4-week MPA program showed a positive effect of the MPA with differences between LF and HF groups. The MPA was more effective in MS patients with LF in cognitive functions, functional status, and postural stability but among HF patients in an emotional state, especially in MS patients below 65 years, although in total, both groups benefited from the MPA.

中文翻译：

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适度的个体化体育活动对多发性硬化症疲劳患者的功能、认知、情绪状态和姿势稳定性的影响

多发性硬化症 (MS) 是一种慢性疾病，疲劳综合征是主要症状之一。本研究的目的是证明适度的体力活动 (MPA) 可能对姿势稳定性、平衡和临床参数产生有益影响。研究组由 137 名在罗兹医科大学神经康复科住院的随机患者组成。最终，76 名患者符合条件，他们被分为两组——高疲劳（HF）和低疲劳（LF）。参与者接受了两次评估：在为期 4 周的 MPA 计划之前和之后使用：扩展残疾状态量表 (EDSS)、疲劳严重程度量表 (FSS)、简易精神状态检查 (MMSE)、蒙特利尔认知评估 (MoCA) 、贝克抑郁量表 (BDI) 和老年抑郁量表 (GDS)，并进行了稳定性平台测试。4 周 MPA 计划后获得的结果显示 MPA 的积极作用与 LF 和 HF 组之间的差异。MPA 对 LF 的 MS 患者在认知功能、功能状态和姿势稳定性方面更有效，但在处于情绪状态的 HF 患者中，尤其是在 65 岁以下的 MS 患者中，尽管总的来说，两组都受益于 MPA。