A carboxylate-type liquid zwitterion, OE₂imC₃C, has been recently reported as a unique solvent as a class of ionic liquids with distinctive properties and functions such as cellulose dissolution ability and low toxicity to fermentative microoganisms. Therefore, OE₂imC₃C first enabled successive conversion of biomass to bioethanol in the same reaction pot. However, the reagent, 1-bromo-2-(2-methoxyethoxy)ethane, used for OE₂imC₃C synthesis is expensive and sometimes out of production and thus prevents its industrialization. Here we synthesized OE₂imC₃C from general and low-cost reagents. We also confirmed that the present OE₂imC₃C maintained the distinctive properties and functions because previous literature indicates synthetic procedures affect the properties. The low toxicity and cellulose dissolution ability of the OE₂imC₃C synthesized in this study were equivalent to those of conventional OE₂imC₃C. In addition, OE₂imC₃C is known to have ability to cryopreserve mammalian cells and the OE₂imC₃C synthesized in this study exhibited the ability.

最近报道了羧酸盐型液体两性离子 OE ₂ imC ₃ C 作为一种独特的溶剂作为一类具有独特性质和功能的离子液体，例如纤维素溶解能力和对发酵微生物的低毒性。因此，OE ₂ imC ₃ C 首先能够在同一个反应罐中将生物质连续转化为生物乙醇。然而，用于OE ₂ imC ₃ C合成的试剂1-溴-2-(2-甲氧基乙氧基)乙烷价格昂贵且有时会停产，因此阻碍了其工业化。在这里，我们从通用和低成本试剂合成了 OE ₂ imC ₃ C。我们还确认目前的 OE₂ imC ₃ C 保持了独特的特性和功能，因为以前的文献表明合成程序会影响这些特性。本研究合成的 OE ₂ imC ₃ C 的低毒和纤维素溶解能力与常规 OE ₂ imC ₃ C相当。此外，已知OE ₂ imC ₃ C 具有冷冻保存哺乳动物细胞和 OE 的能力本研究合成的₂ imC ₃ C表现出这种能力。