There are several studies reporting the outcomes of hypoplastic aortic arch and aortic coarctation repair with combination of techniques. However, only few studies reported of aortic arch and coarctation repair using a homograft patch through sternotomy and circulatory arrest with retrograde cerebral perfusion. We report our experience and outcomes of this cohort of neonates and infants.

We performed retrospective data collection for all neonates and infants who underwent aortic arch reconstruction between 2015 and 2020 at our institute. Data are presented as median and inter-quartile range (IQR).

The cohort included 76 patients: 49 were males (64.5%). Median age at operation was 16 days (IQR 9–43.25 days). Median weight was 3.5 kg (IQR 3.10–4 kg). There was no 30 days mortality. Three patients died in hospital after 30 days (3.95%), neurological adverse events occurred in only one patient (1.32%) and recurrent laryngeal nerve injury was noted in four patients (5.26%). Only three patients required the support of extracorporeal membrane oxygenation (ECMO) with a median ECMO run of 4 days. Median follow-up was 35 months (IQR 18.9–46.4 months); 5 years survival was 93.42% (n = 71). The rate of re-intervention on the aortic arch was 9.21% (n = 7).

Our experience shows excellent outcomes in repairing aortic arch hypoplasia with homograft patch under moderate to deep hypothermia with low in-hospital and 5 years mortality rates.

有几项研究报告了结合技术的主动脉弓发育不全和主动脉缩窄修复的结果。然而，只有少数研究报道了通过胸骨切开术和逆行脑灌注停循环使用同种移植补片修复主动脉弓和缩窄。我们报告了我们对这组新生儿和婴儿的经验和结果。

我们对 2015 年至 2020 年间在我院接受主动脉弓重建的所有新生儿和婴儿进行了回顾性数据收集。数据表示为中位数和四分位数间距 (IQR)。

该队列包括 76 名患者：49 名男性（64.5%）。手术年龄中位数为 16 天（IQR 9-43.25 天）。体重中位数为 3.5 公斤（IQR 3.10-4 公斤）。没有30天死亡率。30天后住院死亡3例（3.95%），仅1例（1.32%）出现神经系统不良事件，4例（5.26%）出现喉返神经损伤。只有 3 名患者需要体外膜肺氧合 (ECMO) 支持，中位 ECMO 运行时间为 4 天。中位随访时间为 35 个月（IQR 18.9-46.4 个月）；5 年生存率为 93.42%（n = 71）。主动脉弓再介入率为 9.21%（n = 7）。

我们的经验表明，在中度至深低温下用同种移植物补片修复主动脉弓发育不全，住院死亡率和 5 年死亡率低。