Background and objectives

Behavioral therapies such as the Comprehensive Behavioral Intervention for Tics (CBIT) are recommended as the first-line treatment for Tourette's Disorder. This treatment approach is comprised of three central components: habit reversal training, functional assessment/intervention, and relaxation training. Despite its combined efficacy, the contribution of each therapeutic component in CBIT for reducing tic severity remains undetermined. The study evaluated the efficacy of relaxation training alone or alongside other CBIT components for reducing tic severity.

Methods

In this multiple-baseline study, participants completed a baseline assessment (A), 4 weekly sessions of relaxation training followed by a posttreatment assessment (B), 8 weekly sessions of CBIT followed by a posttreatment assessment (C), and a 1 month posttreatment follow up assessment (D). Six participants (83% male) aged 10–18 with Tourette's Disorder completed study procedures. Primary outcomes of tic severity was the Yale Global Tic Severity Scale (YGTSS).

Results

A repeated measures ANOVA revealed a significance reduction in tic severity over time (p = .010). While post-hoc tests revealed a moderate non-significant reduction in tic severity after relaxation training (d =.23), large significant reductions in tic severity were observed after the combined treatment of relaxation training and CBIT (d = 1.17) that were maintained at a 1-month follow-up visit (d = 1.53).

Limitations

Findings are limited by the small sample size.

Conclusions

While relaxation training is effective when included in conjunction with CBIT, relaxation training alone is not effective in reducing tic severity in patients with Tourette's Disorder.

中文翻译：

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抽动症抽动综合行为干预和抽动症综合行为干预的放松训练：参与者连续病例系列的多重基线

背景和目标

建议将诸如抽动综合行为干预 (CBIT) 等行为疗法作为妥瑞氏症的一线治疗方法。这种治疗方法由三个核心部分组成：习惯逆转训练、功能评估/干预和放松训练。尽管具有综合疗效，但 CBIT 中每种治疗成分对降低抽动严重程度的贡献仍未确定。该研究评估了放松训练单独或与其他 CBIT 组件一起降低抽动严重程度的效果。

方法

在这项多基线研究中，参与者完成了基线评估 (A)、每周 4 次放松训练和治疗后评估 (B)、每周 8 次 CBIT 和治疗后评估 (C) 以及 1 个月的治疗后后续评估 (D)。六名患有图雷特氏症的 10-18 岁参与者（83% 男性）完成了研究程序。抽动严重程度的主要结果是耶鲁全球抽动严重程度量表（YGTSS）。

结果

重复测量 ANOVA 显示随着时间的推移抽动严重程度显着降低 ( p  = .010)。虽然事后测试显示放松训练后抽动严重程度有适度的非显着降低（d =.23），但在保持放松训练和 CBIT（ d  = 1.17）的联合治疗后观察到抽动严重程度显着降低在 1 个月的随访中 ( d  = 1.53)。

限制

研究结果受到样本量小的限制。

结论

虽然放松训练与 CBIT 结合使用是有效的，但单独的放松训练不能有效降低抽动症患者的抽动严重程度。