Inflammatory markers are associated with quality of life, physical activity, and gait speed but not sarcopenia in aged men (40–79 years),Journal of Cachexia, Sarcopenia and Muscle

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Inflammatory markers are associated with quality of life, physical activity, and gait speed but not sarcopenia in aged men (40–79 years)
Journal of Cachexia, Sarcopenia and Muscle ( IF 8.9 ) Pub Date : 2021-09-15 , DOI: 10.1002/jcsm.12785
Jolan Dupont _{1,

2} , Leen Antonio ₃ , Lenore Dedeyne ₁ , Terence W O'Neill ₄ , Dirk Vanderschueren ₃ , Giulia Rastrelli ₅ , Mario Maggi ₆ , György Bártfai ₇ , Felipe F Casanueva _{8,

9} , Aleksander Giwercman ₁₀ , Jolanta Słowikowska-Hilczer ₁₁ , Margus Punab ₁₂ , Ilpo T Huhtaniemi _{13,

14} , Frederick C W Wu ₁₅ , Jos Tournoy _{1,

2} , Katrien Koppo ₁₆ , Evelien Gielen _{1,

2}

Affiliation

Geriatrics and Gerontology, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
Department of Geriatric Medicine, UZ Leuven, Leuven, Belgium.
Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Centre for Epidemiology Versus Arthritis, The University of Manchester, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester, UK.
Andrology, Women's Endocrinology and Gender Incongruence Unit, Mario Serio 'Department of Experimental and Clinical Biomedical Sciences', University of Florence, Florence, Italy.
Endocrinology Unit, Mario Serio 'Department of Experimental and Clinical Biomedical Sciences', University of Florence, Florence, Italy.
Department of Obstetrics, Gynaecology and Andrology, Albert Szent-Györgyi Medical University, Szeged, Hungary.
Department of Medicine, Santiago de Compostela University, Complejo Hospitalario Universitario de Santiago (CHUS), Santiago, Spain.
CIBER de Fisiopatología Obesidad y Nutricion (CB06/03), Instituto Salud Carlos III, Santiago de Compostela, Santiago, Spain.
Department of Translational Medicine, Lund University, Malmö, Sweden.
Department of Andrology and Reproductive Endocrinology, Medical University of Lodz, Łódź, Poland.
Andrology Unit, United Laboratories of Tartu University Clinics, Tartu, Estonia.
Department of Metabolism, Digestion and Reproduction, Institute of Reproductive and Developmental Biology, Imperial College London, London, UK.
Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, Turku, Finland.
Department of Endocrinology, Manchester Royal Infirmary, The University of Manchester, Manchester, UK.
Exercise Physiology Research Group, Department of Movement Sciences, KU Leuven, Leuven, Belgium.

Age-related chronic low-grade inflammation (inflammaging) is one of the proposed mechanisms behind sarcopenia. However, findings regarding inflammatory markers in sarcopenic older adults are conflicting. This study aimed to determine the association between inflammatory markers, prevalent as well as incident sarcopenia, sarcopenia-defining parameters, quality of life (QoL), and physical activity in middle-aged and older men.

中文翻译：

炎症标志物与老年男性（40-79 岁）的生活质量、身体活动和步速有关，但与肌肉减少症无关

与年龄相关的慢性低度炎症（炎症）是肌肉减少症背后的拟议机制之一。然而，关于肌肉减少的老年人炎症标志物的发现是相互矛盾的。本研究旨在确定中年和老年男性的炎症标志物、普遍的以及偶发的肌肉减少症、肌肉减少症定义参数、生活质量 (QoL) 和身体活动之间的关联。

更新日期：2021-09-15

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