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Impact of red blood cell distribution width and mean platelet volume in patients with ST-segment elevation myocardial infarction
Heart and Vessels ( IF 1.4 ) Pub Date : 2021-09-13 , DOI: 10.1007/s00380-021-01936-6
Toshiaki Ebina 1 , Shiori Tochihara 1 , Mai Okazaki 1 , Kazuyo Koike 1 , Yuko Tsuto 1 , Megumi Tayama 1 , Yukiko Takanami 1 , Haruka Hirose 1 , Mutsuo Horii 1, 2 , Kozo Okada 2 , Yasushi Matsuzawa 2 , Nobuhiko Maejima 2 , Noriaki Iwahashi 2 , Kiyoshi Hibi 2 , Masami Kosuge 2 , Kouichi Tamura 3 , Kazuo Kimura 2
Affiliation  

The complete blood cell count is one of the most frequently ordered laboratory tests, and many parameters, including red blood cell distribution width (RDW) and mean platelet volume (MPV), are available. The purpose of this study was to investigate the usefulness of the combination of RDW and MPV in patients with ST-segment elevation myocardial infarction (STEMI). Patients with STEMI who underwent primary percutaneous coronary intervention were retrospectively enrolled (n = 229). The association between RDW as well as MPV and cardiovascular events was investigated. The median age was 67 years, and males made up 85% of the sample. Median RDW was 13.6%, and median MPV was 8.2 fL. During a median follow-up period of 528 days (IQR 331.5–920.5), 41 patients died or experienced major adverse cardiac and cerebrovascular events (MACCEs). Patients with RDW ≧ 13.7% had more deaths or MACCEs with marginal significance (p = 0.0799). Patients with MPV ≧ 8.3 fL had significantly more deaths or MACCEs (p = 0.0283). Patients with RDW ≧ 13.7% and MPV ≧ 8.3 fL had significantly more deaths or MACCEs (p = 0.0185). MPV was significantly associated with death or adverse events in patients with STEMI who were treated with primary PCI. RDW had only a weak association with death or adverse events. The results of the combination of MPV and RDW were similar to those of MPV.



中文翻译:

ST段抬高型心肌梗死患者红细胞分布宽度和平均血小板体积的影响

全血细胞计数是最常用的实验室检查之一,有许多参数可用,包括红细胞分布宽度 (RDW) 和平均血小板体积 (MPV)。本研究的目的是探讨 RDW 和 MPV 联合治疗 ST 段抬高型心肌梗死 (STEMI) 患者的有效性。回顾性纳入接受初次经皮冠状动脉介入治疗的 STEMI 患者(n = 229)。研究了 RDW 以及 MPV 和心血管事件之间的关联。中位年龄为 67 岁,男性占样本的 85%。中位 RDW 为 13.6%,中位 MPV 为 8.2 fL。在 528 天(IQR 331.5-920.5)的中位随访期间,41 名患者死亡或经历了主要的心脑血管不良事件(MACCEs)。RDW ≥ 13.7% 的患者有更多的死亡或 MACCE,具有边际显着性 ( p  = 0.0799)。MPV ≥ 8.3 fL 的患者死亡或 MACCE 显着增加 ( p  = 0.0283)。RDW ≥ 13.7% 和 MPV ≥ 8.3 fL 的患者死亡或 MACCE 显着增加(p = 0.0185)。MPV 与接受直接 PCI 治疗的 STEMI 患者的死亡或不良事件显着相关。RDW 与死亡或不良事件的关联很小。MPV和RDW组合的结果与MPV相似。

更新日期:2021-09-13
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