Increasing the vulnerability of plants especially crops to a wide range of cold stress reduces plant growth, development, yield production, and plant distribution. Cold stress induces physiological, morphological, biochemical, phenotypic, and molecular changes in plants. Transcription factor (TF) is one of the most important regulators that mediate gene expression. TF is activated by the signal transduction pathway, together with cis-acting element modulate the transcription of cold-responsive genes which contribute to increasing cold tolerance in plants. Here, AP2/ERF TF family is one of the most important cold stress-related TF families that along with other TF families, such as WRKY, bHLH, bZIP, MYB, NAC, and C2H2 interrelate to enhance cold stress tolerance. Over the past decade, significant progress has been found to solve the role of transcription factors (TFs) in improving cold tolerance in plants, such as omics analysis. Furthermore, numerous studies have identified and characterized the complexity of cold stress mechanisms among TFs or between TFs and other factors (endogenous and exogenous) including phytohormones, eugenol, and light. The role, function, and relationship among these TFs or between TFs and other factors to enhance cold tolerance still need to be clarified. Here, the current study analysed the role of AP2/ERF TF and the linkages among AP2/ERF with MYB, WRKY, bZIP, bHLH, C2H2, or NAC against cold stress tolerance.

增加植物尤其是农作物对各种冷胁迫的脆弱性会降低植物的生长、发育、产量和植物分布。冷胁迫会引起植物的生理、形态、生化、表型和分子变化。转录因子（TF）是介导基因表达的最重要的调节因子之一。TF通过信号转导途径被激活，与顺式作用元件一起调节冷响应基因的转录，从而有助于提高植物的耐冷性。其中，AP2/ERF TF 家族是最重要的冷应激相关 TF 家族之一，与其他 TF 家族（如 WRKY、bHLH、bZIP、MYB、NAC 和 C2H2）相互关联以增强冷应激耐受性。在过去的十年中，在解决转录因子（TF）在提高植物耐冷性方面的作用方面已经取得了重大进展，例如组学分析。此外，大量研究已经确定并表征了转录因子之间或转录因子与其他因素（内源性和外源性）（包括植物激素、丁子香酚和光）之间冷应激机制的复杂性。这些转录因子之间或转录因子与其他增强耐寒因子之间的作用、功能和关系仍有待阐明。本研究分析了 AP2/ERF TF 的作用以及 AP2/ERF 与 MYB、WRKY、bZIP、bHLH、C2H2 或 NAC 对抗冷应激耐受性的联系。