Blood Neurofilament Light Chain in Genetic Ataxia: A Meta-Analysis,Movement Disorders

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Blood Neurofilament Light Chain in Genetic Ataxia: A Meta-Analysis
Movement Disorders ( IF 7.4 ) Pub Date : 2021-09-14 , DOI: 10.1002/mds.28783
Linliu Peng ₁ , Shang Wang ₁ , Zhao Chen _{1,

2,

3,

4} , Yun Peng ₁ , Chunrong Wang ₅ , Zhe Long ₆ , Huirong Peng ₁ , Yuting Shi ₁ , Xuan Hou ₁ , Lijing Lei ₁ , Linlin Wan ₁ , Mingjie Liu ₁ , Guangdong Zou ₁ , Lu Shen _{1,

2,

3,

4} , Kun Xia _{7,

8} , Rong Qiu ₉ , Beisha Tang _{1,

2,

3,

4} , Tetsuo Ashizawa _{10,

11} , Thomas Klockgether _{12,

13} , Hong Jiang _{1,

2,

3,

4,

14}

Affiliation

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.
National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, China.
Hunan International Scientific and Technological Cooperation Base of Neurodegenerative and Neurogenetic Diseases, Changsha, China.
Department of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Department of Neurology, The Second Xiangya Hospital, Central South University, Changsha, China.
Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Hunan Key Laboratory of Medical Genetics, Central South University, Changsha, China.
School of Computer Science and Engineering, Central South University, Changsha, China.
Neuroscience Research Program, Houston Methodist Research Institute, Houston, Texas, USA.
Stanley H. Appel Department of Neurology, Weill Cornell Medicine at Houston Methodist Hospital, Houston, Texas, USA.
Department of Neurology, University of Bonn, Bonn, Germany.
German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
School of Basic Medical Science, Central South University, Changsha, China.

No comprehensive meta-analysis has ever been performed to assess the value of neurofilament light chain (NfL) as a biomarker in genetic ataxia.

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