Differences in platelet-rich plasma composition influence bone healing,Journal of Clinical Periodontology

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Differences in platelet-rich plasma composition influence bone healing
Journal of Clinical Periodontology ( IF 5.8 ) Pub Date : 2021-09-13 , DOI: 10.1111/jcpe.13546
Faez Saleh Al-Hamed ₁ , Lina Abu-Nada ₁ , Rania Rodan ₁ , Stylianos Sarrigiannidis ₂ , Jose Luis Ramirez-Garcialuna _{3,

4} , Hanan Moussa _{1,

5} , Osama Elkashty _{1,

6} , Qiman Gao ₁ , Tayebeh Basiri ₁ , Laura Baca ₇ , Jesus Torres ₇ , Lisa Rancan ₈ , Simon D Tran ₁ , Marie Lordkipanidzé _{9,

10} , Mari Kaartinen ₁ , Zahi Badran _{11,

12} , Faleh Tamimi ₁₃

Affiliation

Faculty of Dentistry, McGill University, Montreal, Canada.
Centre for the Cellular Microenvironment, School of Engineering, University of Glasgow, Glasgow, UK.
Faculty of Medicine, McGill University, Montreal, Canada.
The Bone Engineering Labs, Research Institute McGill University Health Center, Montreal, Canada.
Faculty of Dentistry, Benghazi University, Benghazi, Libya.
Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Dental Clinical Specialities Department, Faculty of Dentistry, Complutense University, Madrid, Spain.
Department of Biochemistry & Molecular Biology, Faculty of Medicine, Complutense University of Madrid, Madrid, Spain.
Faculté de Pharmacie, Université de Montréal, Montreal, Canada.
Research Center, Montreal Heart Institute, Montreal, Canada.
Department of Periodontology (CHU/Rmes Inserm U1229/UIC11), Faculty of Dental Surgery, University of Nantes, Nantes, France.
College of Dental Medicine, University of Sharjah, Sharjah, UAE.
College of Dental Medicine, Qatar University, Doha, Qatar.

Platelet-rich plasma (PRP) is an autologous blood-derived material that has been used to enhance bone regeneration. Clinical studies, however, reported inconsistent outcomes. This study aimed to assess the effect of changes in leucocyte and PRP (L-PRP) composition on bone defect healing.

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