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Determinants of early antibody responses to COVID-19 mRNA vaccines in exposed and naive healthcare workers
medRxiv - Infectious Diseases Pub Date : 2021-09-12 , DOI: 10.1101/2021.09.08.21263232
Gemma Moncunill , Ruth Aguilar , Marta Ribes , Natalia Ortega , Rocío Rubio , Gemma Salmeron , María José Molina , Marta Vidal , Diana Barrios , Robert A. Mitchell , Alfons Jimenez , Cristina Castellana , Pablo Hernández-Luis , Pau Rodo , Susana Méndez , Anna Llupiá , Laura Puyol , Natalia Rodrigo Melero , Carlo Carolis , Alfredo Mayor , Luis Izquierdo , Pilar Varela , Antoni Trilla , Anna Vilella , Sonia Barroso , Ana Angulo , Pablo Engel , Marta Tortajada , Alberto L. García-Basteiro , Carlota Dobaño

Background Two doses of mRNA vaccination have shown >94% efficacy at preventing COVID-19 mostly in naive adults, but it is not clear if the second dose is needed to maximize effectiveness in those previously exposed to SARS-CoV-2 and what other factors affect responsiveness.

中文翻译:

暴露和幼稚医护人员对 COVID-19 mRNA 疫苗的早期抗体反应的决定因素

背景两剂 mRNA 疫苗接种已显示在预防 COVID-19 的有效性 > 94%,主要是在未感染的成年人中,但尚不清楚是否需要第二剂以最大限度地提高先前暴露于 SARS-CoV-2 的人的有效性,以及还有哪些其他因素影响反应能力。
更新日期:2021-09-14
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