Basilar artery occlusion stroke is known to have poor outcome with a high rate of morbidity and mortality despite best medical therapy. Since the original report of intra-arterial therapy for basilar artery occlusion in 1983, two recent randomized trials comparing endovascular therapy versus best medical management were completed on a large scale, BASICS (Basilar Artery International Cooperation Study) and the BEST trial (Basilar Artery Occlusion Endovascular Intervention Versus Standard Medical Treatment), both of which demonstrated equivocal benefit of the two modalities. In this commentary, we comment and highlight important lessons related to basilar occlusion stroke as learned from the BASICS and BEST randomized trials.

中文翻译：

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基底动脉闭塞性脑卒中的血管内治疗

尽管进行了最佳的药物治疗，但已知基底动脉闭塞性卒中预后不良，发病率和死亡率很高。自 1983 年首次报道基底动脉闭塞的动脉内治疗以来，最近完成了两项大规模比较血管内治疗与最佳药物治疗的随机试验，BASICS（基底动脉国际合作研究）和 BEST 试验（基底动脉闭塞）血管内干预与标准医疗），两者都证明了这两种方式的模棱两可的好处。在这篇评论中，我们评论并强调了从 BASICS 和 BEST 随机试验中获得的与基底动脉闭塞性卒中相关的重要教训。