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Hydrogen sulphide in liver glucose/lipid metabolism and non-alcoholic fatty liver disease
European Journal of Clinical Investigation ( IF 5.5 ) Pub Date : 2021-09-14 , DOI: 10.1111/eci.13680
Inês Mateus 1 , Carina Prip-Buus 1
Affiliation  

For a long time, hydrogen sulphide (H2S) was considered only as a toxic gas, inhibiting mitochondrial respiration at the level of cytochrome c oxidase, and an environmental pollutant. Nowadays, H2S is recognized as the third mammalian gasotransmitter, playing an important role in inflammation, septic shock, ischaemia reperfusion events, cardiovascular disease and more recently in liver physiology and chronic liver diseases such as non-alcoholic fatty liver disease (NAFLD).

中文翻译:

肝脏葡萄糖/脂质代谢和非酒精性脂肪肝中的硫化氢

长期以来,硫化氢(H 2 S)仅被认为是一种有毒气体,在细胞色素c氧化酶水平上抑制线粒体呼吸,是一种环境污染物。如今,H 2 S 被认为是哺乳动物的第三种气体递质,在炎症、感染性休克、缺血再灌注事件、心血管疾病以及最近在肝脏生理学和慢性肝病如非酒精性脂肪性肝病 (NAFLD) 中发挥重要作用.
更新日期:2021-09-14
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