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Intestinal-derived HDL: The portal guardian of the liver
Immunity ( IF 25.5 ) Pub Date : 2021-09-14 , DOI: 10.1016/j.immuni.2021.08.010
Sheng Chen 1 , Di Wang 2
Affiliation  

The trafficking and function of intestine-derived high-density lipoprotein (HDL) have not been identified. In a recent issue of Science, Han et al. (2021) find that intestine-derived HDL neutralizes intestinal-leaked LPS in the portal vein, serving as a host disease tolerance strategy to restrain liver damage of enteric origin under physiological conditions.



中文翻译:

肠源性高密度脂蛋白:肝脏的门户守护者

肠源性高密度脂蛋白 (HDL) 的运输和功能尚未确定。在最近一期的《科学》杂志上,Han 等人。(2021) 发现肠源性高密度脂蛋白中和门静脉中肠漏出的 LPS,作为宿主疾病耐受策略,在生理条件下抑制肠源性肝损伤。

更新日期:2021-09-14
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