The trafficking and function of intestine-derived high-density lipoprotein (HDL) have not been identified. In a recent issue of Science, Han et al. (2021) find that intestine-derived HDL neutralizes intestinal-leaked LPS in the portal vein, serving as a host disease tolerance strategy to restrain liver damage of enteric origin under physiological conditions.

中文翻译：

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肠源性高密度脂蛋白：肝脏的门户守护者

肠源性高密度脂蛋白 (HDL) 的运输和功能尚未确定。在最近一期的《科学》杂志上，Han 等人。(2021) 发现肠源性高密度脂蛋白中和门静脉中肠漏出的 LPS，作为宿主疾病耐受策略，在生理条件下抑制肠源性肝损伤。