The utility of brain-based biomarkers for psychiatric disorders hinges among other factors on their ability to explain a significant portion of the phenotypic variance. In particular, many small scale studies have been unable to arbitrate whether structural or functional magnetic resonance imaging has potential to be a biological marker for these disorders.

中文翻译：

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神经影像学测量与情感症状之间关联的影响大小：荟萃分析

用于精神疾病的基于大脑的生物标志物的效用取决于它们解释表型差异的重要部分的能力。特别是，许多小规模研究无法判断结构或功能磁共振成像是否有可能成为这些疾病的生物标志物。