Higher Trimethylamine-N-Oxide Plasma Levels with Increasing Age Are Mediated by Diet and Trimethylamine-Forming Bacteria,mSystems

当前位置： X-MOL 学术 › mSystems › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Higher Trimethylamine-N-Oxide Plasma Levels with Increasing Age Are Mediated by Diet and Trimethylamine-Forming Bacteria
mSystems ( IF 5.0 ) Pub Date : 2021-09-14 , DOI: 10.1128/msystems.00945-21
Silke Rath ₁ , Katharina Rox _{2,

3} , Sven Kleine Bardenhorst ₄ , Ulf Schminke ₅ , Marcus Dörr _{6,

7} , Julia Mayerle ₈ , Fabian Frost ₉ , Markus M Lerch ₉ , André Karch ₄ , Mark Brönstrup ₂ , Dietmar H Pieper ₁ , Marius Vital _{1,

10}

Affiliation

Microbial Interactions and Processes Research Group, Helmholtz Centre for Infection Researchgrid.7490.a, Braunschweig, Germany.
Department of Chemical Biology, Helmholtz Centre for Infection Researchgrid.7490.a, Braunschweig, Germany.
German Center for Infection Research (DZIF), Hannover-Braunschweig Site, Helmholtz Center for Infection Research, Braunschweig, Germany.
Institute of Epidemiology and Social Medicine, University of Münstergrid.5949.1, Münster, Germany.
Department of Neurology, University Medicine Greifswald, Greifswald, Germany.
Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.
German Centre for Cardiovascular Research (DZHK) partner site Greifswald, Greifswald, Germany.
Department of Medicine II, University Hospital Munich, Ludwig-Maximillian University Munich, Munich, Germany.
Department of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Institute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.

Many cohort studies have investigated the link between diet and plasma TMAO levels, reporting incongruent results, while gut microbiota were only recently included into analyses. In these studies, taxonomic data were recorded that are not a good proxy for ...

中文翻译：