Gut Metabolites Are More Predictive of Disease and Cohoused States than Gut Bacterial Features in a Polycystic Ovary Syndrome-Like Mouse Model,mSystems

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Gut Metabolites Are More Predictive of Disease and Cohoused States than Gut Bacterial Features in a Polycystic Ovary Syndrome-Like Mouse Model
mSystems ( IF 5.0 ) Pub Date : 2021-09-14 , DOI: 10.1128/msystems.01149-20
Bryan Ho ₁ , Daniel Ryback ₂ , Basilin Benson ₁ , Cayla N Mason ₁ , Pedro J Torres ₂ , Robert A Quinn _{3,

4} , Varykina G Thackray ₅ , Scott T Kelley _{1,

2}

Affiliation

Using a combination of untargeted metabolomics and metagenomics, we performed a comparative longitudinal analysis of the feces collected in a cohousing study with a PCOS-like mouse model. Our results showed that gut metabolite composition experienced ...

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