In vitro activity of bedaquiline and imipenem against actively growing, nutrient-starved, and intracellular Mycobacterium abscessus,Antimicrobial Agents and Chemotherapy

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In vitro activity of bedaquiline and imipenem against actively growing, nutrient-starved, and intracellular Mycobacterium abscessus
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2021-09-13 , DOI: 10.1128/aac.01545-21
Olumide Martins ₁ , Jin Lee ₁ , Amit Kaushik ₁ , Nicole C Ammerman _{1,

2} , Kelly E Dooley ₁ , Eric L Nuermberger ₁

Affiliation

Mycobacterium abscessus lung disease is difficult to treat due to intrinsic drug resistance and the persistence of drug-tolerant bacteria. Currently, the standard of care is a multi-drug regimen with at least 3 active drugs, preferably including a β-...

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