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Pharmacokinetic and Safety Profile of the Novel HIV Non-Nucleoside Reverse Transcriptase Inhibitor MK-8507 in Adults without HIV
Antimicrobial Agents and Chemotherapy ( IF 4.9 ) Pub Date : 2021-09-13 , DOI: 10.1128/aac.00935-21
Wendy Ankrom 1 , Deanne Jackson Rudd 1 , Andrea Schaeffer 1 , Deborah Panebianco 1 , Evan J Friedman 1 , Charles Tomek 2 , S Aubrey Stoch 1 , Marian Iwamoto 1
Affiliation  

MK-8507 is a novel HIV-1 non-nucleoside reverse transcriptase inhibitor in clinical development with potential for once-weekly oral administration for the treatment of HIV-1 infection. Two randomized, double-blind, placebo-controlled phase 1 studies in ...

中文翻译:

新型 HIV 非核苷逆转录酶抑制剂 MK-8507 在非 HIV 成人中的药代动力学和安全性特征

MK-8507 是一种处于临床开发阶段的新型 HIV-1 非核苷逆转录酶抑制剂,具有每周一次口服治疗 HIV-1 感染的潜力。两项随机、双盲、安慰剂对照的 1 期研究...
更新日期:2021-09-14
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