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The antimicrobial peptide MK58911-NH2 acts on planktonic, biofilm and intramacrophage cells of Cryptococcus neoformans
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2021-09-13 , DOI: 10.1128/aac.00904-21
Junya de Lacorte Singulani 1 , Lariane Teodoro Oliveira 1 , Marina Dorisse Ramos 1 , Nathália Ferreira Fregonezi 1 , Paulo César Gomes 1 , Mariana Cristina Galeane 1 , Mario Sergio Palma 2 , Ana Marisa Fusco Almeida 1 , Maria José Soares Mendes Giannini 1
Affiliation  

Cryptococcosis is associated with high rates of morbidity and mortality, especially in AIDS patients. Its treatment is carried out by combining amphotericin B and azoles or flucytosine, which cause unavoidable toxicity issues to the host. Thus, the ...

中文翻译:

抗菌肽 MK58911-NH2 作用于新型隐球菌的浮游、生物膜和巨噬细胞内

隐球菌病与高发病率和死亡率有关,尤其是在艾滋病患者中。它的治疗是通过将两性霉素 B 和唑类或氟胞嘧啶结合起来进行的,这会对宿主造成不可避免的毒性问题。就这样 ...
更新日期:2021-09-14
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