Cerium enriched magnetic dual-acid nanocatalyst (CoFe₂O₄@SiO₂@APTES@ATA-CeCl₃) as green and recoverable nanocatalyst was prepared. The novel nanocatalyst was characterized by Fourier transform infrared spectroscopy (FT-IR), powder X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), inductively coupled plasma atomic emission spectrometry (ICP-AES), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), nitrogen absorption-desorption experiment, and vibrating sample magnetometer (VSM). The dual-acid nanocatalyst was able to efficiently catalyze the synthesis of functionalized 1,5-benzodiazepines following through a three-component domino reaction of various substituted o-phenylenediamine, 1,3-dicarbonyl compounds, and phenylacetaldehyde. The dual-acid sites of Brønsted acid (2-aminoterephthalic acid (ATA)) and Lewis acid (CeCl₃) of the catalysts were determinant features. Furthermore, a plausible catalytic mechanism has been proposed. The dual-acid nanocatalyst can be simply separated and reused without any remarkable decrease within the yield after six runs.

富含铈的磁性双酸纳米催化剂（CoFe ₂ O ₄ @SiO ₂ @APTES@ATA-CeCl ₃) 作为绿色且可回收的纳米催化剂被制备。通过傅里叶变换红外光谱（FT-IR）、粉末X射线衍射（XRD）、扫描电子显微镜（SEM）、能量色散X射线光谱（EDS）、电感耦合等离子体原子发射光谱（ ICP-AES)、透射电子显微镜 (TEM)、X 射线光电子能谱 (XPS)、氮吸脱附实验和振动样品磁强计 (VSM)。该双酸纳米催化剂能够通过各种取代的o的三组分多米诺反应有效催化功能化 1,5-苯二氮卓类化合物的合成。-苯二胺、1,3-二羰基化合物和苯乙醛。催化剂的布朗斯台德酸（2-氨基对苯二甲酸（ATA））和路易斯酸（CeCl ₃）的双酸位点是决定性特征。此外，还提出了一种合理的催化机制。双酸纳米催化剂可以简单地分离和重复使用，六次运行后产率没有任何显着下降。