The development of automatized hyphenated systems is attractive to avoid sampling error, save time and reduce costs. Among these systems, on-line SFE-SFC allows the extraction, the separation, and the detection of molecules in an efficient, quick and eco-friendly way. After a historical introduction and explanation on the use of supercritical fluids for extraction or analysis, principles of supercritical fluid extraction (SFE) and supercritical fluid chromatography (SFC) will be presented. Partially-supercritical on-line systems (e.g. SFE-liquid chromatography) will be compared before discussing about the evolution of on-line SFE-SFC over the past decades. Given the significance of the hyphenation between SFE and SFC to achieve a successful transfer, different devices will be examined to gain a better understanding of the coupling challenges and to determine the most advantageous configuration.

自动化连字符系统的开发对于避免采样错误、节省时间和降低成本具有吸引力。在这些系统中，在线 SFE-SFC 允许以高效、快速和环保的方式提取、分离和检测分子。在对使用超临界流体进行萃取或分析的历史进行介绍和解释之后，将介绍超临界流体萃取 (SFE) 和超临界流体色谱 (SFC) 的原理。在讨论过去几十年在线 SFE-SFC 的演变之前，将比较部分超临界在线系统（例如 SFE-液相色谱）。鉴于 SFE 和 SFC 之间的连字对于实现成功转移的重要性，