The immune system is composed of immune organs, immune cells, and immunoactive substances, which plays a vital role in antitumor immunity in cancer immunotherapy. During the process of the antitumor immune response, many factors are involved in the cancer immune cycle. Therefore, developing intelligent strategies based on the steps of the cancer immune cycle to elicit the immune responses for enhanced cancer immunotherapy is of great significance. In this review, the key factors in each step of the cancer immune cycle are discussed, and then, the intelligent therapeutic strategies for modulating the immune surveillance against cancer are highlighted. Considering the demand for cancer immunotherapy in clinic, some suggestions for constructing new intelligent strategies are also put forward, which will make antitumor immunity more effective and advance the development of cancer immunotherapy.

中文翻译：

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基于免疫周期的癌症免疫治疗策略

免疫系统由免疫器官、免疫细胞和免疫活性物质组成，在癌症免疫治疗中的抗肿瘤免疫中起着至关重要的作用。在抗肿瘤免疫反应的过程中，许多因素都参与了癌症免疫循环。因此，开发基于癌症免疫循环步骤的智能策略以引发免疫反应以增强癌症免疫治疗具有重要意义。在这篇综述中，讨论了癌症免疫循环每个步骤中的关键因素，然后重点介绍了调节癌症免疫监视的智能治疗策略。考虑到临床对癌症免疫治疗的需求，也提出了构建新的智能策略的一些建议，