Human induced pluripotent stem cells (hIPSCs) are an important tool, but challenges remain in optimizing their use. hIPSC cultures frequently become contaminated and overrun with cells containing genetic aberrations. In this issue of Developmental Cell, Price et al. establish that this results from cell competition between wild-type and variant cells.

中文翻译：

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人类多能干细胞培养中的机械细胞竞争

人类诱导多能干细胞（hIPSC）是一种重要的工具，但优化其使用仍面临挑战。 hIPSC 培养物经常受到含有遗传畸变的细胞的污染和泛滥。在本期《发育细胞》中，Price 等人。确定这是野生型细胞和变异细胞之间的细胞竞争的结果。