Background: Human papillomavirus (HPV) infections are sexually transmitted and most frequently associated with cervical cancer in women, but they are also a public health concern in men. There is rising evidence that HPV’s role in other cancers, such as anal, vulva, vaginal, penis, head, and neck cancers. The present study aimed to understand the factors associated with HPV and cervical cancer knowledge levels of university students before and after an educational intervention.
Methods: An Institutional-based cross-sectional study was conducted from October to November 2018. A total of 638 study participants were selected using a simple random multistage sampling technique. A pretested questionnaire was used, consolidated the data, and analyzed with SPSS version 23. Bivariate and multivariate logistic regression analyses were performed to identify which variables were associated with the knowledge levels.
Results: Six hundred thirty-eight study participants with a 100% response rate, and the mean age was 21.07 years (±SD, 1.96). Initial awareness of various broad categories was 4.09, and after the intervention, it increased to 23.4, with an average increase of 19.31 at 99% CI, p≤ 0.001 significance level. Before the educational intervention, students with < 21 years of age [6.16, 95% CI: (2.21– 17.18)] and ≤ 2.5 CGPA [3.44, 95% CI: (1.51– 7.81)] were less knowledgeable over other counterparts. After educational intervention, the year of study was significantly associated with increased knowledge of overall and different broad categories of cervical cancer and HPV. Year of study, 1st-year students [AOR: 0.27, 95% CI: (0.14– 0.51)] over third years and above are less knowledgeable. First-year students and CGPA ≤ 2.5 were less improved awareness over others.
Conclusion: The educational intervention improved more than fourfold increase knowledge on cervical cancer and HPV, and the year of study was a key factor associated with overall improvement. This study suggests that educational intervention effectively strengthens our understanding of the spread of HPV and cervical cancer disease burden.



中文翻译：

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埃塞俄比亚西北部男女大学生教育干预前后HPV和宫颈癌知识水平的相关因素


背景：人乳头瘤病毒（HPV）感染通过性传播，最常与女性宫颈癌相关，但它们也是男性的公共卫生问题。越来越多的证据表明 HPV 在其他癌症中发挥作用，如肛门癌、外阴癌、阴道癌、阴茎癌、头颈癌。本研究旨在了解教育干预前后大学生 HPV 和宫颈癌知识水平的相关因素。

方法： 2018 年 10 月至 11 月进行了一项基于机构的横断面研究。采用简单随机多阶段抽样技术，总共选择了 638 名研究参与者。使用预先测试的问卷，整合数据，并使用 SPSS 23 版进行分析。进行双变量和多变量逻辑回归分析，以确定哪些变量与知识水平相关。

结果： 638 名研究参与者的应答率为 100%，平均年龄为 21.07 岁（±SD，1.96）。各种大类的初始认知度为4.09，干预后提升至23.4，99% CI 时平均提升19.31，p≤0.001显着性水平。在教育干预之前，年龄 < 21 岁 [6.16，95% CI：(2.21–17.18)] 和 ≤ 2.5 CGPA [3.44，95% CI：(1.51–7.81)] 的学生的知识水平低于其他学生。经过教育干预后，学习年份与对宫颈癌和 HPV 的整体和不同大类知识的增加显着相关。学习年份，一年级学生[AOR：0.27，95% CI：(0.14–0.51)]三年级及以上的学生知识较少。一年级学生和 CGPA ≤ 2.5 的意识改善程度低于其他学生。

结论：教育干预使人们对宫颈癌和 HPV 的了解提高了四倍以上，并且学习年份是与整体改善相关的关键因素。这项研究表明，教育干预有效地加强了我们对 HPV 传播和宫颈癌疾病负担的了解。